Hi All, For our next Statistical Bioinformatics Seminar on Monday, we will be hosting Dr. Pengyi Yang from the University of Sydney. The seminars are held at 1:00 pm on Mondays at the Charles Perkins Centre, Level 3 Large meeting room. The format of the talk is approximately 40 minutes plus discussion. Further information can be found on the website https://www.maths.usyd.edu.au/u/SemConf/StatisticalBioinformatics.html Monday October 14th 2019 1:00 PM Seminar Level 3 Large Meeting Room Charles Perkins Centre Title: Systems stem cell biology Abstract: The ability of stem and progenitor cells to differentiate into specialised cells is essential for organogenesis and opens the possibility for regenerative medicine where damaged cells in tissues and organs could be replaced using stem cell-derived cells. The understanding of identities and fates of stem/progenitor cells is the foundation for controlling stem cell differentiation and their use for stem cell-based therapies. In this talk, I will present three studies where systems approaches were utilised to understand cell identities and fate decisions in stem cells and during their differentiation. The talk will showcase how computational methods can be applied for making biological discovery and expanding our knowledge in stem cell biology. About the Speaker: Pengyi Yang is the Group Leader of the Computational Systems Biology group at Childrenâs Medical Research Institute, at the Westmead Research Hub. He also heads the Computational Trans-Regulatory Biology group at Charles Perkins Centre, and holds a Senior Lectureship at the School of Mathematics and Statistics, the University of Sydney. As a systems biologist cross-trained in computer science, statistics, and systems biology, Pengyi combines computational and statistical methods to model trans-regulatory networks in stem and progenitor cells using large-scale multi-layered omic data. Hope to see you there!