Hello all, The next MaPSS talk of this semester will be at 17:00 on Monday 9th in Carslaw 535. It’s a great opportunity to meet fellow postgrads, listen to an interesting talk, and of course get some free pizza! ************************************************************************************** Speaker: Adarsh Kumbhari Title: Using circuits to understand immune self-regulation Abstract: T cells are specialised immune cells responsible for killing pathogens. How these cells are able to self-regulate, however, is unknown. Inspired by analogies with electrical circuts, we develop a mathematical model to infer how immune dynamics are driven by "input signals". We find that T cell expansion may be a change-detection system, both in response to checkpoint and antigen expression, which has implications for immune therapies against cancer. ************************************************************************************** See you there! Details can also be found on the school’s Postgraduate Society website: http://www.maths.usyd.edu.au/u/MaPS/mapss.2020.html Cheers, Eric